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目的探讨广东地区婴儿肝炎综合征中丙型肝炎病毒感染及其传播途径。方法采用酶联免疫吸附法（ELISA法）检测血清中丙型肝炎病毒（HCV）抗体，多聚酶链反应（PCR）检测血清中HCVRNA。结果90例婴肝中有11例HCV标志阳性，阳性率为12．2％（11／90），其中抗HCV以及HCVRNA均阳性4例，单项抗HCV阳性3例，单项HCVRNA阳性4例。母亲抗HCV阳性2例。结论HCV感染是广东地区婴儿肝炎综合征中一个不可忽视的病因，本组11例阳性患者的传播途径主要与输注血制品有关，其次为母婴传播。
Objective To investigate hepatitis C virus infection and its transmission in infantile hepatitis syndrome in Guangdong. Methods Serum samples of hepatitis C virus (HCV) were detected by enzyme-linked immunosorbent assay (ELISA) and HCV RNA was detected by polymerase chain reaction (PCR). Results Of the 90 infants, 11 were positive for HCV, the positive rate was 12.2% (11/90), of which 4 were anti-HCV and HCV RNA positive, 3 were anti-HCV positive and 4 were single HCVRNA. Mother anti-HCV positive in 2 cases. Conclusion HCV infection is an undeniable cause of hepatitis syndrome in infants in Guangdong Province. The positive transmission of 11 positive cases in this group is mainly related to blood transfusion, followed by mother-to-child transmission.