论文部分内容阅读
Serum fetuin-A levels are reportedly elevated in hyperthyroidism. However, there are few relevant epidemiologic studies. We conducted a cross-sectional study in Songnan community, China in 2009 to investigate the association between serum fetuin-A concentrations and thyroid function. A total of 2,984 participants aged 40 years and older were analyzed. Multivariable linear regression analysis revealed that serum fetuin-A concentrations were positively associated with log(free triiodothyronine) and were inversely associated with log(thyroid peroxidase antibody) after adjustment(both P < 0.05). Compared with the participants in the lowest tertile of free triiodothyronine and free thyroxine level, those in the highest tertile had higher fetuin-A concentrations. Additionally, high serum fetuin-A concentrations were related to high thyroid function(odds ratio 1.27, 95% confidence interval 1.01-1.61), after adjustment for conventional risk factors.
Serum fetuin-A levels are reportedly elevated in hyperthyroidism. However, there are few relevant epidemiologic studies. We conducted a cross-sectional study in Songnan community, China in 2009 to investigate the association between serum fetuin-A concentrations and thyroid function. A total Multivariable linear regression analysis revealed that serum fetuin-A concentrations were positively associated with log (free triiodothyronine) and were inversely associated with log (thyroid peroxidase antibody) after adjustment (both P <0.05) Compared with the participants in the lowest tertile of free tertiodofyrandine and free thyroxine level, those in the highest tertile had higher fetuin-A concentrations. confidence interval 1.01-1.61), after adjustment for conventional risk factors.