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作者在前两年中见到7个易患黑色素瘤的家庭,这些家庭都具有明显的遗传综合征,表现为一种高危不典型的皮肤黑色素细胞损害。26名病人黑色素瘤的诊断,4名由尸检所证实,5名由医院记录证实,17名由病理检查证实。作者对7个家庭中的63名成人进行了检查,其中42名有明显的色素性皮肤损害。皮损为扁平状,直径通常超过10毫米,偶尔染上黑色,兰色,粉红色,有时色素减少。每人的皮损数目从10个到100个以上不等,于颈部和上肢最为常见,也可见于身体不暴露的
In the previous two years, the authors saw seven predominantly melanoma-prone families, all with marked genetic syndromes characterized by a high-risk, atypical cutaneous melanocytic lesion. 26 patients diagnosed with melanoma, 4 confirmed by autopsy, 5 confirmed by the hospital records, 17 confirmed by pathological examination. The authors examined 63 adults in 7 families, of whom 42 had marked pigmented skin lesions. Lesions flattened, usually more than 10 mm in diameter, and occasionally infected with black, blue, pink, and sometimes reduce the pigment. The number of lesions per person ranging from 10 to more than 100, the most common in the neck and upper limbs can also be seen in the body is not exposed