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目的:通过对无锡地区773名体检的育龄妇女硫酸脱氢表雄酮(DHEAS)与性激素结合球蛋白(SHBG)正常参考水平调查,了解无锡地区育龄妇女体内雄激素代谢情况,为诊治多囊卵巢综合征提供实验室依据。方法:以无锡地区2008年9月～2009年6月来无锡市妇幼保健院体检的773名育龄妇女为对象,取血采用电化学发光法查血DHEAS和SHBG水平。结果:无锡地区育龄妇女DHEAS和SHBG因年龄而异,20～24岁DHEAS正常参考值是(282.5±124.5)μg/ml,25～34岁DHEAS正常参考值是(219.4±120.6)μg/ml,34～44岁DHEAS正常参考值是(198.9±138.0)μg/ml,SHBG 20～24岁(43.5±16.5)nom/ml,25～34岁正常参考值是(60.5±28.8)nom/ml,34～44岁正常参考值是(83.9±26.1)nom/ml。结论:无锡地区妇女不同年龄DHEAS和SHBG的正常参考值水平存在一定差异。
OBJECTIVE: To investigate the status of androgen metabolism in women of childbearing age in Wuxi from 773 women in childbearing age in Wuxi, and to investigate the normal reference levels of DHEAS and SHBG. Syndrome to provide laboratory evidence. Methods: A total of 773 women of childbearing age who came to Wuxi MCH from September 2008 to June 2009 were enrolled in this study. Blood samples were collected for the detection of DHEAS and SHBG by electrochemiluminescence. Results: The DHEAS and SHBG of women of childbearing age in Wuxi varied with age, the normal reference value of DHEAS was (282.5 ± 124.5) μg / ml for 20-24 years old, (219.4 ± 120.6) μg / ml for 25-34 years old, The normal reference values for DHEAS between 34 and 44 years old were (198.9 ± 138.0) μg / ml and SHBG between 20 and 24 years old (43.5 ± 16.5) nom / ml, and the normal reference values between 25 and 34 years old were (60.5 ± 28.8) The normal reference value of ~ 44 years old was (83.9 ± 26.1) nom / ml. Conclusion: There are some differences in the normal reference values of DHEAS and SHBG among women of different ages in Wuxi.