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目的：探讨晚期喉癌患者喉切除术后保留喉发声功能以提高生存质量。方法：对17例晚期喉癌行喉近全切除术（Pearson手术），手术中，保留一侧构状软骨及一条宽约1．5cm的与气管相连的粘膜条形成发声管。N0期患者常规探查颈动脉分叉处淋巴结，根据冰冻病检结果而决定是否行颈淋巴清扫术。结果：术后12例发声良好。除1例外均无明显误吸现象。2年、3年及5年生存率分别为70．6％、62．4％、50％。结论：Pearson手术成功的关键是正确施行颈廓清术，坚持肿瘤切除的原则，达到保留晚期喉癌患者的发声功能，提高患者生存率及生存质量。
Objective: To investigate the preservation of throat vocal function after laryngectomy in patients with advanced laryngeal cancer in order to improve the quality of life. METHODS: Seventeen patients with advanced laryngeal carcinoma underwent near-total laryngectomy (Pearson surgery). During the operation, one-sided cartilage was preserved and a tube with a width of approximately 1.5 cm was attached to the trachea to form a sound tube. Patients with stage N0 routinely explore the lymph nodes in the bifurcation of the carotid artery and determine whether or not to perform a neck dissection based on the results of the frozen pathology. Results: 12 cases had good sound after operation. Except for 1 exception, there was no apparent aspiration. The 2-, 3-, and 5-year survival rates were 70.6%, 62.4%, and 50%, respectively. Conclusion: The key to the success of Pearson surgery is the correct implementation of neck dissection, adhere to the principle of tumor resection, to achieve the preservation of vocal function in patients with advanced laryngeal cancer, improve patient survival and quality of life.