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本文将１２例肝硬化并发胃十二指肠溃疡穿孔病人和同期治疗的无肝硬化溃疡穿孔病人进行比较。表明大部分单纯溃疡穿孔者经保守疗法可治愈，而肝硬化组有其临床特点，剧烈腹痛和典型腹膜刺激征较少见（Ｐ＜０．０５），伴发上消化道出血者多见（Ｐ＜０．０５），穿孔直径大，渗液多，非手术疗法不易成功，合并腹水者不易与自发性细菌性腹膜炎相鉴别，死亡率高。指出该病确诊后单纯修补术是一种较安全的方法。
In this paper, 12 patients with cirrhosis complicated with gastroduodenal ulcer perforation and concurrent treatment of non-cirrhotic patients with ulcer perforation were compared. The results showed that most of the simple perforation perforation patients were cured by conservative treatment. However, the clinical features of cirrhosis group were less severe (P <0.05), severe abdominal pain and typical peritoneal irritation were more common in patients with upper gastrointestinal bleeding P <0.05), large perforation diameter, exudate, non-surgical treatment is not easy to succeed, with ascites and spontaneous bacterial peritonitis is not easy to distinguish, high mortality. Pointed out that the diagnosis of simple repair of the disease is a safer method.