论文部分内容阅读
Much epidemiological evidence has linked low birthweight with late cardiovascu lar risk. We measured aortic wall thickness (a marker of early atherosclerosis) by ultrasonography in 25 newborn babies with intrauterine growth restriction and 25 with normal birthweight. Maximum aortic thicknesses were significantly highe r in the babies with intrauterine growth restriction (810 μm [SD 113]) than in those without (743 μm [76], p=0.02), more so after adjustment for birthweight ( 300 μm/kg [45] vs 199 μm/kg [29], p<0.0001). Newborn babies with growth restri ction have significant aortic thickening, suggesting that prenatal events might predispose to later cardiovascular risk.
Much epidemiological evidence has linked low birthweight with late cardiovascu lar risk. We measured aortic wall thickness (a marker of early atherosclerosis) by ultrasonography in 25 newborn babies with intrauterine growth restriction and 25 with normal birthweight. Maximum aortic thicknesses were significantly highe r in the babies with intrauterine growth restriction (810 μm [SD 113]) than in those without (743 μm [76], p = 0.02), more so after adjustment for birthweight (300 μm / kg [45] vs 199 μm / kg ], p <0.0001). Newborn babies with growth restri ction have significant aortic thickening, suggesting that prenatal events might predispose to later cardiovascular risk.