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为探讨乳腺癌保守手术后放疗对局部复发率和生存率的影响及确定局部复发的低危人群,作者对1984年～1989年间数家治疗机构的837例淋巴结阴性的乳腺癌在肿物切除和腋淋巴结清扫术后随机分为放疗组(416例)与对照组(421例),条件为肿物直径≤4cm;切缘阴性;淋巴结阴性。术后12周开始放疗,采用~(60)Co全乳腺切线位对穿野照射4000cGy/16次/3周,然后原发部位局部补充1250cGy/5次。所
To investigate the effect of radiotherapy on the local recurrence rate and survival rate after conservative surgery for breast cancer and to identify low-risk populations with local recurrence, the authors performed tumor resection on 837 node-negative breast cancers at several treatment facilities between 1984 and 1989. After axillary lymph node dissection, they were randomly divided into radiotherapy group (416 cases) and control group (421 cases), with the condition of tumor diameter ≤ 4cm; negative margin; negative lymph node. Radiotherapy was started 12 weeks after surgery. The whole breast tangential position of ~(60)Co was used to irradiate the field with 4000 cGy/16 times/3 weeks. Then the primary site was supplemented with 1250 cGy/5 times. By