目的:探讨纳洛酮和氨茶碱配伍治疗小儿急性呼吸衰竭的临床效果。方法:选取我院收治的80例小儿急性呼吸衰竭患儿,以随机数表抽取法将其分为对照组和观察组各40例,对照组给予对症支持治疗,观察组给予纳洛酮和氨茶碱配伍治疗,对两组患儿治疗效果进行观察对比。结果:观察组患儿PaO_2、SaO_2明显高于对照组,Pa CO_2明显低于对照组,且观察组治疗总有效率明显高于对照组,P<0.05。结论:针对小儿急性呼吸衰竭患儿给予纳洛酮和氨茶碱配伍治疗可明显改善患儿血气指标,提高整体治疗水平,值得在临床上大力推广。 Objective: To investigate the clinical effect of compatibility of naloxone and aminophylline in the treatment of pediatric acute respiratory failure. Methods: A total of 80 children with acute respiratory failure admitted to our hospital were enrolled in this study. They were divided into control group and observation group by random number table. Each group was given symptomatic and supportive treatment. The observation group was given naloxone and ammonia Theophylline compatibility treatment, treatment of children with two groups were observed and compared. Results: PaO_2 and SaO_2 in the observation group were significantly higher than those in the control group, PaCO_2 was significantly lower than that in the control group, and the total effective rate in the observation group was significantly higher than that in the control group (P <0.05). Conclusion: The combination of naloxone and aminophylline in infants with acute respiratory failure can significantly improve the blood gas index and improve the overall level of treatment, which is worth to be popularized clinically.