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目的:探讨生长抑素联合乌司他丁在重症急性胰腺炎治疗中的应用价值。方法:将我院近一年收治的88例重症急性胰腺炎患者按照随机数字表法分为两个组别,实验组与参照组各44例。为实验组患者使用生长抑素联合乌司他丁治疗,对参照组患者使用生长抑制素治疗,比较两组患者的治疗总有效率及病情好转时间。结果:实验组患者的治疗总有效率较比参照组更高,实验组腹痛缓解时间、腹胀缓解时间以及血AMS、尿AMS、WBC恢复时间对比参照组更快,均P<0.05。结论:应用生长抑素联合乌司他丁治疗重症急性胰腺炎效果理想,可快速缓解临床症状、改善实验室指标,值得推广。
Objective: To investigate the value of somatostatin combined with ulinastatin in the treatment of severe acute pancreatitis. Methods: Eighty-eight cases of severe acute pancreatitis admitted to our hospital in recent one year were divided into two groups according to the random number table. The experimental group and the reference group were 44 cases each. The patients in the experimental group were treated with somatostatin combined with ulinastatin, and the patients in the reference group were treated with somatostatin. The total effective rate of treatment and the improvement of disease duration were compared between the two groups. Results: The total effective rate of treatment group was higher than that of the reference group. The pain relief time, abdominal distension time, blood AMS, urinary AMS and WBC recovery time in the experimental group were faster than those in the reference group (all P <0.05). Conclusion: The combination of somatostatin and ulinastatin in treatment of severe acute pancreatitis is effective and can quickly relieve clinical symptoms and improve laboratory indicators, which is worthy of popularization.