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目的分析埃索美拉唑联合莫沙必利治疗反流性食管炎患者临床疗效。方法选取2013年7月至2014年4月在我院治疗的78例反流性食管炎患者,随机分成对照组和实验组,每组39例。对照组采用埃索美拉唑治疗;实验组采用埃索美拉唑、莫沙必利联合治疗。观察两组治疗的有效率和在胃腔镜下病灶的愈合程度以及不良反应发生情况。结果实验组的临床有效率(97.44%)明显高于对照组(71.79%);实验组的胃镜下反流性食管炎愈合有效率(92.31%)明显好于对照组(66.67%),差异有显著性(P<0.05)。结论埃索美拉唑联合莫沙必利治疗反流性食管炎效果明显。
Objective To analyze the clinical efficacy of esomeprazole combined with mosapride in the treatment of patients with reflux esophagitis. Methods Seventy-seven patients with reflux esophagitis treated in our hospital from July 2013 to April 2014 were randomly divided into control group and experimental group, with 39 cases in each group. The control group was treated with esomeprazole; the experimental group was treated with esomeprazole and mosapride. Observe the efficiency of the two groups of treatment and the degree of healing of the lesions under the endoscope and the occurrence of adverse reactions. Results The clinical effective rate (97.44%) in experimental group was significantly higher than that in control group (71.79%). The healing rate of endoscopic esophagogastrostomy in experimental group (92.31%) was significantly better than that in control group (66.67%), Significance (P <0.05). Conclusion Esomeprazole combined with mosapride treatment of reflux esophagitis effect is obvious.