目前 ,国内外许多国家已对军队实施重组酵母乙肝疫苗预防接种 ,但推荐的标准剂量有较大差别 ,按 0、1、6个月免疫程序 ,国内普遍采用 3次 5 μg方案[1] ,欧美国家则采用 3次 2 0 μg方案[2 ] 。为探讨适合我军入伍新兵的合适剂量 ,我们对 5 μg、10 μg、15 μg、2 0 μg四个剂 At present, many countries at home and abroad have already carried out the vaccination of recombinant hepatitis B vaccines against the army, but the recommended standard doses are quite different. According to the immunization schedule of 0, 1 and 6 months, 3 5 μg programs are commonly used in China [1] Europe and the United States adopted 3 times 20 g program [2]. In order to explore the appropriate dose for recruits to our military, we evaluated 5 μg, 10 μg, 15 μg, 20 μg, four doses