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自1986年5月加拿大魁北克省推广应用一种新的麻疹、腮腺炎和风疹三联疫苗(Trivirix)后,发现4例儿童在接种该疫苗后19~26天罹患脑膜脑炎。为此,作者对所在医院15年中诊断为腮腺炎脑膜脑炎的所有病例作了回顾性研究,并评价了结果及其与疫苗的相关性。在1973~1988年的15年中,共发生腮腺炎脑膜脑炎24例。1973~1977年为16例,1978~1985年为3例,1986~1988年为5例。其中4例发生在接种腮腺炎疫苗(Urabe Am 9株)后19~26天。
Since the introduction of a new measles, mumps and rubella Trivirix vaccine in Quebec, Canada, in May 1986, four children were found to have meningoencephalitis 19 to 26 days after the vaccine was administered. To this end, the authors undertook a retrospective study of all cases diagnosed as mumps meningoencephalitis in their hospital for 15 years and evaluated the results and their relevance to the vaccine. In the 15 years from 1973 to 1988, there were 24 cases of mumps meningoencephalitis. From 1973 to 1977, 16 cases were from 1978 to 1985, 3 cases from 1986 to 1988, 5 cases. Four of these occurred 19 to 26 days after the mumps vaccine (Urabe Am 9 strain).