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目的：观察西沙必利治疗新生儿胃潴留的疗效。方法：随机将８０例新生儿胃潴留患儿分成二组，西沙必利组４０例，男２２例，女１８例，孕周３７８５±２６７，出生体重（ｋｇ）３１５±０５７。用西沙必利片０３－０６ｍｇｋｇ－１ｄ－１，ｉｇ或ｐｏ分成了３次（间隔８小时给药一次），疗程２周；对照组４０例，男１９例，女２１例，孕周３７８５±２８７，出生体重（ｋｇ）３１８±０４６。除治疗原发病外，不给任何药物治疗。二组皆以每次喂奶前抽吸胃内残留的奶汁的量作为评价疗效的指标。结果：疗程结束后，西沙必利组胃潴留的治愈率９７５％较对照组５７５％显著增高（ｘ２＝１８．３５，Ｐ＜０．０１）。结论：西沙必利治疗新生儿胃潴留有明显疗效。
Objective: To observe the efficacy of cisapride in the treatment of neonatal gastric retention. Methods: 80 cases of neonatal gastric retention were randomly divided into two groups, 40 cases of cisapride group, 22 males and 18 females, gestational age 37 85 ± 2 67, birth weight (kg) 3 15 ± 0 57. Cisapride tablets 0 3-0 6mg kg-1 d-1, ig or po divided into 3 times (interval of 8 hours administered once) for 2 weeks; the control group of 40 patients, 19 males, Female 21 cases, gestational age 37 85 ± 2 87, birth weight (kg) 3 18 ± 0 46. In addition to the treatment of primary disease, do not give any drug treatment. In both groups, the amount of milk remaining in the stomach before each feeding was used as an index to evaluate the curative effect. Results: After treatment, the cure rate of gastric retention in cisapride group was significantly higher than that in control group (97.5% vs 57.5%, x2 = 18.35, P <0.01). Conclusion: cisapride treatment of neonatal gastric retention has a significant effect.