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目的对脑卒中后继发性癫痫的发病机制、发作特点以及治疗方法进行探讨和研究。方法对660例于2006年3月至2012年11月间在本院进行脑卒中治疗的患者进行回顾性分析,其中,50例患者继发癫痫,研究和分析脑卒中病灶部位、类型、发病率以及癫痫类型和发作时间。结果蛛网膜下腔与脑出血继发癫痫发病率差异不具有统计学意义(P>0.05),脑梗死继发癫痫发病率要明显低于蛛网膜下腔与脑出血,差异具有统计学意义(P<0.05)。基底节区继发癫痫发病率低于蛛网膜下腔和皮质区,差异具有统计学意义(P<0.05),蛛网膜下腔继发癫痫发病率低于皮质区,差异具有统计学意义(P<0.05)。结论脑卒中病灶部位以及类型与脑卒中后继发性癫痫的发病率具有一定的关系,对早发型与迟发型患者应该分别采取短期治疗与长期治疗的不同治疗方式。
Objective To explore the pathogenesis of post-stroke secondary epilepsy, characteristics of attack and treatment methods. Methods A retrospective analysis was performed on 660 patients with stroke treated in our hospital from March 2006 to November 2012. Among them, 50 patients had epilepsy secondary to the study and analysis of the location, type and incidence of stroke As well as the type and duration of epilepsy. Results There was no significant difference in the incidence of epilepsy between subarachnoid and intracerebral hemorrhage (P> 0.05). The incidence of epilepsy secondary to cerebral infarction was significantly lower than that of subarachnoid and intracerebral hemorrhage (P <0.05) P <0.05). The incidence of epilepsy secondary to basal ganglia was lower than that of the subarachnoid and cortical areas (P <0.05), and the incidence of epilepsy secondary to subarachnoid space was lower than that of the cortex (P <0.05). The difference was statistically significant (P <0.05). Conclusion The location and type of stroke lesions have a certain relationship with the incidence of secondary epilepsy after stroke. Different treatment methods should be taken for short-term and long-term treatment for early-onset and late-onset patients respectively.