糖耐量减低(impairedglucosetolerance,IGT)是正常糖耐量向糖尿病发展的过渡阶段。此时已存在糖代谢异常,其特点为餐后高血糖。IGT的危害主要在于:IGT患者已存在胰岛素分泌和作用的缺陷,具有发生 2型糖尿病的倾向;IGT患者发生大血管病变、微血管病变的危险性亦增加。研究发 Impaired glucose tolerance (IGT) is a transitional period between the development of normal glucose tolerance and diabetes mellitus. At this point there have been abnormal glucose metabolism, which is characterized by postprandial hyperglycemia. The harm of IGT mainly lies in the fact that IGT patients have the defects of insulin secretion and function and have the tendency to develop type 2 diabetes. The incidence of macrovascular disease and microvascular disease in IGT patients also increases. Research and development