β阻滞剂的概念早在19世纪末人们就知道,药物要发挥作用必须与组织的某一“部位”结合,这个结合部位称为受体,它是一种蛋白质。一种神经冲动的传导需要传出神经冲动的传递物,这种传递物称为介质。1648年AhlQuist从交感神经末梢分离出两种不同的传递物,且在效应器官存在两种受体,即α与β受体。受体对神经介质具有高度的选择性。在付 The concept of beta blockers As early as the late 19th century people knew that drugs must play a role in the organization with a “site” combination, the binding site called the receptor, it is a protein. Conduction of a nerve impulse requires the delivery of a nerve impulse transfer, which is called the medium. In 1648 AhlQuist isolated two different transmitters from the sympathetic nerve terminals, and there are two receptors in the effector organ, the alpha and beta receptors. Receptors are highly selective for neurotransmitters. Pay