近年来,由于现代农业和环境保护对农药的要求日益提高,已经由传统的杀死转变成为生物调控。杂环化合物由于其多变的结构和广泛的生物活性使得在农药的开发中受到广泛的关注,尤其是含氮杂环。1,2,4-三唑类化合物因具有除草、杀菌、杀虫、抗癌、抗炎、抗菌、抗惊厥等多样性的生物活性而受到广泛关注。一些含1,2,4-三唑环的化合物已经开发成功许多商品化的农药和医药(图1),如除 In recent years, due to the increasing demand for pesticides in modern agriculture and environmental protection, the traditional killing has changed into a biological control. Heterocyclic compounds have attracted extensive attention in the development of pesticides due to their variable structure and extensive biological activity, especially nitrogen-containing heterocycles. 1,2,4-Triazole compounds have attracted extensive attention for their biological activities such as weeding, sterilization, insecticide, anticancer, anti-inflammatory, antibacterial and anticonvulsant. Some 1,2,4-triazole ring-containing compounds have been developed successfully for many commercial pesticides and pharmaceuticals (Figure 1)