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随着经济发展和人们生活水平的提高,近年来,心血管疾病发病率、死亡率呈逐年上升趋势,其中,冠心病(CHD)已成为发达国家人口主要死亡原因。因此,对冠心病患者危险程度的评估及高危患者的识别临床显得尤为重要。随着分子免疫学及生物学等相关基础学科的快速发展。细胞粘附分子(cell adhesion moleculesCAMs)在冠心病危险分层中的作用日渐受到重视。本文就此结合文献作一综述。1 细胞粘附分子的概述细胞粘附分子是指一类调节细胞与细胞间、细胞与细胞基质间相互结合,起粘附作用的膜表面糖蛋白。它
With the economic development and the improvement of people’s living standards, the incidence of cardiovascular diseases and mortality have been increasing year by year. Among them, coronary heart disease (CHD) has become the leading cause of death in developed countries. Therefore, the assessment of the degree of risk in patients with coronary heart disease and high-risk patients with clinical identification is particularly important. With the rapid development of basic disciplines such as molecular immunology and biology. The role of cell adhesion molecules (CAMs) in the risk stratification of coronary heart disease has received increasing attention. This article is a summary of the literature. 1 Overview of cell adhesion molecules Cell adhesion molecules refers to a class of membrane surface glycoproteins that regulate cell-cell, cell-cell matrix interactions and adhesion. it