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迄今为止,洋地黄仍是治疗心力衰竭最有价值的药物,对某些类型心律失常(如心房纤颤、室上性心动过速)也有很好的效果,临床上得到广泛应用。洋地黄治疗心力衰竭虽然已经有将近200年的历史,积累了丰富的实践经验,但其毒性反应仍有相当高的发生率。在接受洋地黄治疗的病人中,出现毒性反应的约有20%,其中约有1/3的病人,心律失常是最早的毒性表现,其毒性反应发生率高的原因可能与药物的安全范围小,强力利尿剂的应用,传统的给药方法等因素有关。近年来对洋地黄作用
To date, digitalis is still the most valuable drug for the treatment of heart failure. It has good effect on some types of arrhythmia (such as atrial fibrillation and supraventricular tachycardia) and has been widely used clinically. Digitalis has been nearly 200 years of history and has accumulated a wealth of practical experience in the treatment of heart failure, but its toxicity is still a very high incidence. Approximately 20% of patients receiving digitalis appear to have toxic reactions. Approximately one-third of patients have arrhythmia as the earliest manifestation of toxicity. The reason for the high incidence of toxic reactions may be due to the small safety margin of the drug , Strong diuretic application, the traditional methods of administration and other factors. In recent years the role of digitalis