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采用放射免疫分析法,对31例婴幼儿肺炎合并心衰作血浆β-内啡呔(β-EP)含量检测,并与24例婴幼儿轻型肺炎、22例健康儿童作对照,结果表明,肺炎合并心衰组血浆β-EP显著高于轻型肺炎组(P<0.01),后者显著高于正常对照组(P<0.01).说明β-EP参与了婴幼作肺炎,特别是合并心衰的病理生理过程,提示血浆β-EP含量可作为判断婴幼儿肺炎严重程度的一项指标。
The plasma beta-endorphin (β-EP) levels in 31 infants with pneumonia complicated with heart failure were measured by radioimmunoassay. The results were compared with 24 infants with mild pneumonia and 22 healthy children. The results showed that pneumonia The plasma β-EP in patients with heart failure was significantly higher than that in patients with mild pneumonia (P <0.01), and the latter was significantly higher than that in the control group (P <0.01). These results suggest that β-EP participates in the pneumonia of infants and young children, especially the pathophysiological process of heart failure. It suggests that the plasma β-EP content can be used as an indicator to judge the severity of pneumonia in infants and children.