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目的:探讨两种不同注射速度的规律间断硬膜外泵注（RIEB）和持续性硬膜外输注（CEI）复合患者自控硬膜外镇痛（PCEA）用于分娩镇痛的效果及不良反应。方法:选择上海市长宁区妇幼保健院2017年6月至2019年1月自愿接受分娩镇痛的初产妇255例，按照随机数字表法分为A、B、C三组，每组85例。所有产妇给予硬膜外分娩镇痛，镇痛液配方为0.08%罗哌卡因+0.4 μg/ml舒芬太尼。A组产妇予以CEI模式镇痛，10 ml/h持续输注。B组与C组产妇予以RIEB模式镇痛，自注射首剂后75 min开始，间断1 h给予10 ml镇痛液，其中B组的注射速度为2 ml/min，C组的注射速度为6 ml/min。记录各组镇痛前（Tn 1）、镇痛后1 h（Tn 2）、宫口开大7 ~ 8 cm时（Tn 3）、分娩时（Tn 4）的体温、疼痛视觉模拟量表（VAS）评分、罗哌卡因、舒芬太尼用量和PCEA有效按压次数，比较两组产程时间、镇痛时间、分娩方式、新生儿Apgar评分及不良反应发生情况。n 结果:三组患者各时点体温比较差异无统计学意义（n P>0.05）。三组患者Tn 1、Tn 2时点VAS评分比较差异无统计学意义（n P>0.05），Tn 3、Tn 4时点VAS评分C组0.05）。n 结论:RIEB复合PCEA用于分娩镇痛的效果显著，且泵注速度为6 ml/min可有效减少PCEA追加次数和罗哌卡因用量、舒芬太尼用量，并且未增加不良反应，对产程也无影响。“,”Objective:To compare the effects and adverse reaction of regular intermittent epidural bolus (RIEB) and continuous epidural infusion (CEI) combined with patient-controlled epidural analgesia (PCEA) on labor analgesia.Methods:The clinical data of 255 patients in C.N. Maternity & Infant Health Hospital from June 2017 to January 2019 who had underwent labor analgesia were randomized into group A, B and C, with 85 cases in each group. Epidural analgesia was used for all the patients, through L n 3-4 intervertebral space with 0.08% ropivacaine and 0.4 μg/ml sulfentanylas epidural analgesic solution. In group A, CEI mode of analgesia was applied with 10 ml/h continuous infusion of analgesic solution. In the other two groups, RIEB mode of analgesia was used and after the first dose of 60 min, 10 ml analgesic solution was injected epidural every one hour at the speed of 2 ml/min in group B and 6 ml/min in group C respectively. The body temperature and visual analogue scale (VAS) score before analgesia (T n 1), 60 min after labor anesthesia (Tn 2), at the time of datively cervix to 7-8 cm (Tn 3) and at labor (Tn 4) were compared among three groups. The frequency of PCEA request, ropivacaine consumption, sufentanil consumption, total delivery duration, analgesic time, delivery mode, neonatal Apgar score and adverse reactions were compared too.n Results:The body temperature at each time points had no significant differences (n P>0.05). The VAS scores at Tn 3, Tn 4 in C group was the most highest, and then in B group was more higher, in A group was the lest, and there were significant differences among the three groups [Tn 3: (1.4 ± 0.5) scores <(2.5 ± 0.5) scores <(3.1 ± 0.6) scores; T n 4: (1.8 ± 0.5) scores < (2.8 ± 0.4) scores <(3.7 ± 0.7) scores] ( n P<0.05). The frequency of PCEA request, ropivacaine consumption, sufentanil consumption in C group were lower than those in B group and A group, the levels of above in B group were lower than those in A group, and there were significant differences (n P0.05).n Conclusions:RIEB combined with PCEA is effective in labor analgesia, and the pump speed of 6 ml/min can effectively decrease the need of PCEA and the dosage of analgesics without additional adverse reactions.