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目的 :探索生物节律疗法治疗咳嗽变异性哮喘 (CVA)的近期疗效。方法 :CVA 90例 ,分为生物节律组 5 0例 ,按生物节律分别给予强的松、舒弗美、赛庚啶顿服 ;普通组 40例 ,给予常规氨茶碱、强的松、赛庚啶口服 ,疗程均为一个月。结果 :19例 6岁以上患儿在CVA发作期PEF值均在 80 %预计值以下 ,吸入喘乐宁后 ,复测PEF值平均升高 15 %以上。两组间临床控制率、总有效率 (分别为 45 7%、69 6%和 15 0 %、3 2 5 %)比较 ,差异非常显著 (P均 <0 .0 1)。结论 :CVA主要是中央气道狭窄并存在高气道反应性。生物节律疗法近期疗效明显优于普通疗法
Objective: To explore the short-term curative effect of biological rhythm therapy on cough variant asthma (CVA). Methods: 90 cases of CVA were divided into the biorhythm group of 50 cases, according to the biological rhythm were given prednisone, Sforum, Cyproteridon served; general group of 40 patients given conventional aminophylline, prednisone, race Oral heptyl, treatment for one month. Results: The PEF values of 19 children aged 6 years and above in the CVA episode were below 80% of the predicted value. After inhalation of dialeptin, PEF value of the retest increased more than 15% on average. There was significant difference between the two groups in clinical control rate and total effective rate (45 7%, 69 6% and 15 0%, 32 5% respectively) (P all <0.01). Conclusions: CVA is mainly characterized by central airway stenosis with high airway reactivity. The recent curative effect of biological rhythm therapy is obviously better than that of common therapy