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目的:分析0～6岁小儿肾病综合征的得病情况,以对其进行更好的防治。方法:分析毕节市2009～2010年收治的598例0～6岁患有肾病综合征的患儿的患病年龄、性别、临床表现等,并对其体内锌、铜、钙等微量元素以及尿转铁蛋白进行检测。结果:0～6岁各个年龄段患肾病综合征及男女在患病比例上差异无统计学意义(P>0.05),临床表现主要有尿蛋白、水肿、腹痛等;出现尿蛋白的比例为94.5%,出现水肿的比例为61.0%,出现的腹痛的比例为59.0%。肾病综合征患儿锌、铜、钙的含量低于正常儿童的平均水平,差异有统计学意义(P<0.05);尿转铁蛋白存在流失,与正常儿童的尿转铁蛋白含量差异有统计学意义(P<0.05)。结论:年龄、性别对小儿患肾病综合征的机率影响并不明显,但是肾病综合征患儿锌、铜、钙的含量低于正常儿童的平均水平,其铁代谢也存在异常,临床表现为尿蛋白、水肿、腹痛等。
OBJECTIVE: To analyze the prevalence of nephrotic syndrome in children aged 0 ~ 6 years to provide better prevention and treatment. Methods: The age, gender and clinical manifestations of 598 children with nephrotic syndrome aged 0-6 years admitted in Bijie from 2009 to 2010 were analyzed. The levels of zinc, copper, calcium and other trace elements and urine Transferrin for testing. Results: There were no significant differences in the incidence of nephrotic syndrome and the proportion of men and women in all age groups from 0 to 6 years old (P> 0.05). The main clinical manifestations were urinary protein, edema and abdominal pain. The urinary protein ratio was 94.5 %, The rate of edema was 61.0%, the rate of abdominal pain was 59.0%. The levels of zinc, copper and calcium in children with nephrotic syndrome were lower than those of normal children (P <0.05), and there was a loss of urinary transferrin, which was statistically different from that of normal children Significance (P <0.05). Conclusion: Age and sex have no obvious effect on the incidence of nephrotic syndrome in children. However, the content of zinc, copper and calcium in children with nephrotic syndrome is lower than the average level in normal children. The iron metabolism is also abnormal. The clinical manifestations are urinary Protein, edema, abdominal pain and so on.