论文部分内容阅读
目的分析肥胖并发高脂血症患者肥胖和“脂肪-胰岛轴”指标的年龄差异。方法肥胖并发高脂血症患者664例按年龄分为三组:A组224例,<30岁;B组212例,30~40岁;C组228例,>40岁。比较三组肥胖指标(体重、肥胖度、BMI、体脂百分率)、脂质指标(TC、TG、LDL-C、HDL-C)、“脂肪-胰岛轴”指标[FBG、空腹胰岛素、空腹瘦素(FLP)、胰岛素敏感性指数(ISI)、HOMA-IR和胰岛β细胞功能指数(HOMA-β)]以及植物神经功能指数。结果A组和B组体脂百分率、FBG、HOMA-IR均较C组降低(P<0.05或P<0.01),ISI较C组升高(P<0.05或P<0.01);A组肥胖度、BMI、FLP较C组降低(P<0.05);B组HOMA-β较C组升高(P<0.05)。结论肥胖并发高脂血症患者的年龄与肥胖、“脂肪-胰岛轴”指标均密切相关。
Objective To analyze the age differences of obesity and “fat-islet axis” in obesity complicated with hyperlipidemia. Methods A total of 664 obese patients with hyperlipidemia were divided into three groups according to their ages: group A (224 cases, <30 years); group B (212 cases, 30-40 years); group C (228 cases)> 40 years old. Obesity index (body weight, obesity, BMI and body fat percentage), lipid index (TC, TG, LDL-C and HDL-C) Fasting leptin (FLP), insulin sensitivity index (ISI), HOMA-IR and pancreatic β-cell function index (HOMA-β)] and autonomic nerve function index. Results The percentage of body fat, FBG and HOMA-IR in group A and group B were significantly lower than those in group C (P <0.05 or P <0.01), but those in group C were significantly higher than those in group C (P <0.05 or P <0.01) , BMI and FLP were lower than those in group C (P <0.05). HOMA-β in group B was higher than that in group C (P <0.05). Conclusion The age of patients with obesity and hyperlipidemia is closely related to the obesity and the “fat-islet axis” index.