目的　比较广州市不同工业行业职工的主要死因。方法　将广州市工业系统参照中国卫生监督统计报告表行业分类分为 6个行业 ,以 1989～ 1992年实施职业健康监护系统中建立的 795 4 7名年龄≥ 35岁的工厂职工个体健康档案为基础资料 ,按前瞻性队列研究方法 ,随访至 1998年 12月 31日 ,登记队列中职工的生存状态和死亡原因 ,计算粗死亡率 ,用Cox比例风险模型计算RR及 95 %CI。结果　 (1) 795 4 7名职工中 ,男 4 935 5人、女 30 192人 ,平均年龄 (43.8± 6 .5 )岁 ,6 4 %的职工年龄在 35～4 4岁 ,各行业职工年龄相近 ,相差± 1岁 ;4 1%的职工接触职业有害因素 ,石化行业职业有害因素接触率最高 (5 3.9% ) ,冶金行业次之 ,机械行业最低 (30 .2 % )。 (2 )截至 1998年 12月 31日 ,平均追踪 (8.0±1.3)年 ,共 6 335 10人年 ;共有 15 77名职工死亡 ,总死亡率为 2 4 8.9/ 10万人年 ,其中橡胶行业总死亡率最高 ,其次为冶金和石化行业 ,主要死因为恶性肿瘤、血管疾病和呼吸系统疾病 ,占总死亡人数的 80 .3%。(3)全死因和血管疾病的粗死亡率橡胶行业排第一位 ,恶性肿瘤和呼吸系统疾病粗死亡率则为冶金行业排第一位。 (4)调整各相关因素后 ,以轻工行业为对照 (RR为 1.0 ) ,发现冶金行业的恶性肿瘤和呼吸系统疾病的RR( Objective To compare the main causes of death among workers in different industrial sectors in Guangzhou. Methods The industrial system of Guangzhou was divided into six industries according to the industry classification of China’s health supervision statistical reports. Based on the individual health records of 795 47 industrial workers aged 35 or above established in the occupational health monitoring system from 1989 to 1992 According to a prospective cohort study, follow-up was to December 31, 1998. Survival status and cause of death of workers in the registration queue were calculated. Rough death rates were calculated. Cox proportional hazards model was used to calculate RR and 95% CI. Results (1) Of the 795 4 7 employees, 4,935 were male and 30,192 were female, with an average age of (43.8 ± 6.5) years. Sixty-four percent of workers were between 35 and 44 years of age, The difference between them is ± 1 year old; 4 1% of workers exposed to occupational harmful factors, the contact rate of occupational harmful factors in petrochemical industry is the highest (5 3.9%), followed by metallurgical industry and the lowest in mechanical industry (30.2%). (2) As of December 31, 1998, the average follow-up was (8.0 ± 1.3) years, 6 335 10 person-years; a total of 15 77 workers died and the total death rate was 24.910 million person-years. Among them, the rubber industry Total mortality was the highest, followed by the metallurgical and petrochemical industries, with the main cause of death being malignancies, vascular diseases and respiratory diseases, accounting for 80.3% of the total deaths. (3) Crude death rate and crude death rate of vascular diseases ranked the first in the rubber industry while the crude death rate of malignant tumors and respiratory diseases ranks the first in the metallurgical industry. (4) After adjusting all the relevant factors, taking the light industry as a control (RR = 1.0), we found that the RR of malignant tumors and respiratory diseases in the metallurgical industry (RR