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采用改进的Ｔｒｏｏｓｔ法对９７例正常人、１１６例原发性肝癌（ＰＨＣ）、２１例肝硬化、２１例转移性肝癌、３２例其它消化道恶性肿瘤、１２例肝良性病变患者血清α－Ｌ－岩藻糖苷酶（ＡＦＵ）活性进行了测定。结果ＰＨＣ组血清ＡＦＵ活性明显高于其它各疾病组，更高于正常人组（Ｐ＜０．０１）。对ＰＨＣ诊断敏感性为７５％，特异性为９０．１％，在３６例甲胎蛋白（ＡＦＰ）阴性的ＰＨＣ中，ＡＦＵ阳性率为８０．６％。ＡＦＵ与ＡＦＰ联合检测，可使ＰＨＣ的诊断阳性率提高到９３．９％。
Improved Troost method was used to detect serum α-L in 97 normal persons, 116 primary liver cancer (PHC), 21 liver cirrhosis, 21 metastatic liver cancer, 32 other gastrointestinal cancers, and 12 hepatic benign lesions. - Fucosidase (AFU) activity was measured. Results Serum AFU activity in PHC group was significantly higher than that in other disease groups and higher than normal group (P<0.01). The sensitivity of the diagnosis of PHC was 75%, and the specificity was 90.1%. In 36 cases of AFP-negative PHC, the positive rate of AFU was 80.6%. Combined detection of AFU and AFP can increase the diagnostic positive rate of PHC to 93.9%.