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过敏性休克是过敏性反应的一种表现形式,其发生急速,后果严重。对这一问题的研究不仅有助于对机体反应性理论问题的了解,而且有一定的实践意义。家兔适于进行多种生理学观察,但家兔过敏性休克的形成较为困难;而且,在非致死性休克时,除直接描记血压外,休克的症状也较难观察。因而,有必要对家兔过敏性休克的形成方法进行研究,并寻找一种较为简便的研究指标。我们在实验中观察到,将马血清或鸡蛋清经皮下及静脉给家兔作致敏注射,间隔6—11天(少数动物间隔18天),自静脉内作决定性注射,可使86%之动物发生休克;并经常件有心电图上的变化,可以做为一项研究家兔过敏性休克的指标。
Anaphylactic shock is a manifestation of anaphylactic reactions, which occur rapidly, with serious consequences. The research on this issue not only helps to understand the theory of the body’s reactivity, but also has some practical significance. Rabbits are suitable for a variety of physiological observations, but the formation of rabbits with anaphylactic shock is more difficult; and, in non-fatal shock, in addition to direct description of blood pressure, the symptoms of shock is more difficult to observe. Therefore, it is necessary to study the formation of rabbit anaphylactic shock and to find a more convenient research indicators. We observed in experiments that using horse serum or egg white to sensitize rabbits subcutaneously and intravenously to rabbits, 6-11 days apart (a few animals separated by 18 days), a crucial injection from the vein made the 86% Animals have shock; and often have changes on the ECG can be used as an indicator of anaphylactic shock in rabbits.