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报告18例心脏病儿体外循环心内直视手术期间血浆铜、锌变化的结果。正常对照组的血铜、锌含量分别为16.65±3.59×10~(-3)mmol/L和13.54±4.62×10~(-3)mmol/L。体外循环组的铜、锌含量非常显著低于正常对照组(P<0.01);血浆铜和锌的含量在心肺转流开始后下降,术后缓慢上升,但是,术后锌的含量低于术前水平;Cu/Zn比值术中无明显变化,术后较术前明显增高。文章对上述变化的原因及临床意义进行了简要讨论。
Report of 18 cases of heart disease during cardiopulmonary bypass during open heart surgery in patients with copper and zinc changes in the results. The levels of blood copper and zinc in the normal control group were 16.65 ± 3.59 × 10 -3 mmol / L and 13.54 ± 4.62 × 10 -3 mmol / L, respectively. The contents of copper and zinc in cardiopulmonary bypass group were significantly lower than those in normal control group (P <0.01). The levels of copper and zinc in plasma decreased after cardiopulmonary bypass, and then increased slowly after operation. However, Before the level; Cu / Zn ratio no significant changes during operation, postoperative significantly higher than before. The article briefly discusses the reasons for the above changes and their clinical significance.