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HGPS(Hutchinson-Gilford早老综合征,又名早老症)是早产儿罕见的先天性老化性疾病,发病率为出生婴儿的1/800万,主要为常染色体显性遗传,其基因位于1号染色体上。作者报导的病例是从其出生2.5月后开始随访的。 患婴女,白种人。孕37周出生,体重2800g父母无血缘关系,双亲与一5岁大的同胞身体健康,无类似病史。患婴2.5月大时,体重4800g(第25百分位数),身高54cm(第50百分位数),头围39cm(第50百分位数)。耳垂缺失,躯干、四肢和臀部以及大阴唇均有非凹陷性水
HGPS (Hutchinson-Gilford’s syndrome), a rare congenital sequelae of premature infants, occurs at a rate of 1/8 million infants born, mostly autosomal dominant, whose genes are located on chromosome 1 on. The authors reported cases from the birth 2.5 months after the start of follow-up. Baby girl, Caucasian. Born 37 weeks pregnant, weighing 2800g no blood relationship between parents, parents and a 5-year-old compatriots healthy, no similar history. When infants are 2.5 months old, they weigh 4800g (25th percentile), height 54cm (50th percentile) and head circumference 39cm (50th percentile). Lack of earlobe, trunk, limbs and buttocks and labia majora non-depression of water