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Leukotrienes (LTs) are synthesized from membrane derived arachidonic acid. Downstream of 5-lipoxygenase in the arachidonic acid cascade, leukotriene C4 synthase (LTC4S) catalyses the conjugation of leukotriene A4 (LTA4) with reduced glutathione to form LT
Leukotrienes (LTs) are synthesized from membrane derived arachidonic acid. Downstream of 5-lipoxygenase in the arachidonic acid cascade, leukotriene C4 synthase (LTC4S) catalyses the conjugation of leukotriene A4 (LTA4) with reduced glutathione to form LT