论文部分内容阅读
为了研究血清ＩＣＴＰ、ＰＩＣＰ和ＰＩＩＮＰ的水平与原发性肝癌骨转移的关系，采用放射免疫法检测了５０例原发性肝癌（骨转移３０例，无骨转移２０例）及２０例健康者血清中ＩＣＴＰ、ＰＩＣＰ和ＰＩＮＰ的水平，结果发现，原发性肝癌患者血清ＩＣＴＰ、ＰＩＮＰ显著高于健康者（Ｐ＜０．０１和Ｐ＜０．０５），其中伴骨转移的原发性肝癌血清ＩＣＴＰ、ＰＩＮＰ显著高于无骨转移者（Ｐ＜０．０１），但ＰＩＣＰ则无显著性差异，提示ＩＣＴＰ和ＰＩＮＰ可作为原发性肝癌的预后判断指标，尤其可作为原发性肝癌发生骨转移的判断指标。
In order to study the relationship between serum ICTP, PICP and PIINP levels and bone metastases of primary liver cancer, 50 cases of primary liver cancer (30 cases of bone metastases, 20 cases without bone metastases) and 20 healthy subjects were examined by radioimmunoassay. The levels of ICTP, PICP and PINP in the study found that serum ICTP and PINP levels in patients with primary liver cancer were significantly higher than those in healthy individuals (P<0.01 and P<0.05), among which serum of primary liver cancer with bone metastases ICTP and PINP were significantly higher than those without bone metastasis (P<0.01), but there was no significant difference in PICP, suggesting that ICTP and PINP can be used as prognostic indicators for primary liver cancer, especially as a marker of primary liver cancer. Transfer indicator.