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眼球穿孔伤及其并发症的处理是眼科比较棘手的难题之一,关系到治疗与愈后。除由致伤物所致的损伤与感染外,损伤后的病理、生理过程非常复杂,多伴有体液免疫介质参与介导的体液免疫反应过程。眼球穿孔伤后临床免疫学研究已有文献报道[1,2]。关于高原眼球穿孔伤泪液免疫介质的变化,尚未见报道。我院地处海拔3658m高原,1996-04~2000-05共收治眼球穿孔伤患者54例(57眼),对治疗前后泪液中免疫球蛋白(Ig)与补体C3、C4进行了检测,以探讨高原眼球穿孔伤患者治疗前后泪液免疫功能的变化及意义。
Perforated eye injuries and complications of treatment is one of the more difficult ophthalmology problems, related to the treatment and the more. In addition to injuries caused by the injury and infection, the pathological after injury, the physiological process is very complex, more associated with humoral immune mediators involved in the humoral immune response mediated process. Clinical immunology of perforation after eyeball has been reported in the literature [1,2]. On the plateau eyes perforation tear tear fluid immune mediators, has not been reported. Our hospital is located at an altitude of 3658m plateau, from 1996-04 to 2000-05 were treated 54 eyes of patients with perforated trauma (57 eyes), before and after treatment of immunoglobulin (Ig) and complement C3, C4 were tested to explore Changes and significance of tear immunity in patients with ocular perforation injury at the plateau before and after treatment.