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暴发型休克型流行性脑脊髓膜炎(以下简称暴发型流脑)发病急,病情进展迅速,病死率较高。现将我院治疗本病的具体方法及在治疗过程中应注意的事项介绍如下,仅供参考。在综合性治疗过程中应抓住主要矛盾,全力进行抗休克治疗,防治弥漫性血管内凝血(简称DIG)及纤溶亢进是治疗本病的关键。现重点介绍如下: 一、抗菌治疗首选青霉素与氯霉素静脉给药。剂量和用法:(1)青霉素:首次剂量为10万单位/公斤体重,以后按20万单位/公斤体重/日,分2～4次静脉滴注,病情好转后减量,疗程3～5天。(2)氯霉素:与青霉素联合使用,因其毒性较大,故只作短时间使用,待循环情况好转、有尿后即停用,改用磺胺药
Outbreak of shock meningitis (hereinafter referred to as fulminant meningitis) acute onset, the rapid progress of the disease, higher mortality. Now our hospital for the treatment of this disease and the specific methods should be noted in the treatment process are as follows, for reference purposes only. In the process of comprehensive treatment should seize the main contradictions, full anti-shock treatment, prevention and treatment of diffuse intravascular coagulation (DIG) and fibrinolysis is the key to the treatment of this disease. Now highlights the following: First, antibacterial treatment preferred penicillin and chloramphenicol intravenous administration. Dosage and usage: (1) penicillin: the first dose of 100,000 units / kg body weight, then by 200,000 units / kg body weight / day, divided into 2 to 4 times intravenous infusion, improved condition and reduction, the treatment of 3 to 5 days . (2) chloramphenicol: in combination with penicillin, because of its toxicity, it is only for a short time to be used, to be improved circulation, with urine disabled, switched to sulfa drugs