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目的:观察α-干扰素辅佐治疗病毒性毛细支气管炎的疗效。方法:病毒性毛细支气管炎病儿201例(男性149例,女性52例,年龄6±4mo),用α-干扰素15万-2万U,im,qd,共3-5d。相似病儿183例(男性141例,女性42例,年龄7±5mo),用常规治疗为对照组。结果:治疗组体温恢复正常无数、紫绀消失无数、肺部罗音消失天数及住院无数均短于对照组(P<0.01),未见明显不良反应。结论:α-干扰素辅佐治疗病毒性毛细支气管炎疗效显著。
Objective: To observe the efficacy of α-interferon in the treatment of viral bronchiolitis. Methods: 201 children with viral bronchiolitis (149 males and 52 females, age 6 ± 4 months) were treated with α-interferon 150,000 -2,200 U, im, qd for 3-5 days. 183 cases of similar sick children (141 males and 42 females, age 7 ± 5mo), with conventional treatment as the control group. Results: In the treatment group, the body temperature returned to normal, the number of cyanosis disappeared, the number of days of pulmonary rales disappearing and the number of hospitalizations were shorter than those in the control group (P <0.01). No obvious adverse reactions were found. Conclusion: Alpha interferon adjuvant treatment of viral bronchiolitis significant effect.