恶性疟原虫寄生于宿主红细胞内能主动合成蛋白质、并被运送和镶嵌于红细胞膜上,成为抗原性的靶蛋白。已有研究认为粘附素PfEMP1就是这种蛋白质中的一员,在脑、胎盘和其他器官中,粘附至血管内皮受体(即内皮细胞粘连)和未感染的红细胞(玫瑰花结样)。恶性疟原虫多样性的var基因家 Plasmodium falciparum parasites in the host of red blood cells can actively synthesize protein, and is transported and embedded in the erythrocyte membrane, becoming antigenic target protein. It has been suggested that the adhesin PfEMP1 is a member of this protein that adheres to vascular endothelial receptors (ie, endothelial cell adhesion) and uninfected erythrocytes (rosette-like) in the brain, placenta and other organs, . Var gene family of Plasmodium falciparum diversity