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目的探讨创伤性脑损伤(TBI)后低钠血症的发生特点及其危险因素。方法回顾性分析我院136例中、重度TBI患者的临床资料,主要包括年龄、性别、损伤类型、GCS评分、手术、是否有脑水肿和颅底骨折等,并对上述因素与低钠血症的发生进行卡方检验和多因素Logistic回归分析。结果 136例中、重度TBI患者中有56例发生低钠血症,经多因素Logistic回归分析,TBI后低钠血症的发生与患者的年龄、性别、损伤类型、是否开颅手术无关,而与患者的GCS评分、是否合并脑水肿或颅底骨折关系密切。结论 TBI患者如GCS≤8分、合并有脑水肿或颅底骨折,则易于发生低钠血症,需提前采取预防措施。
Objective To investigate the characteristics and risk factors of hyponatremia after traumatic brain injury (TBI). Methods The clinical data of 136 patients with moderate and severe TBI in our hospital were analyzed retrospectively, including age, gender, type of injury, GCS score, operation, brain edema and skull base fracture. The above factors and hyponatremia The incidence of chi-square test and multivariate logistic regression analysis. Results In 136 cases, 56 cases of severe TBI patients had hyponatremia. Multivariate Logistic regression analysis showed that the incidence of hyponatremia after TBI was not related to the age, sex, type of injury and craniotomy or not. GCS score with patients with or without cerebral edema or skull base fracture are closely related. Conclusions Patients with TBI, such as GCS ≤ 8, have brain edema or skull base fracture with hyponatremia and need preventive measures in advance.