目的　研究飞行对飞行员血清一氧化氮 ( NO)及脂质过氧化的影响。　方法　采用 α-萘乙烯二胺分光光度法、黄嘌呤氧化酶法和硫代巴比妥酸分光光度法测定飞行员的血清 NO、超氧化物歧化酶 ( SOD)和过氧化脂质 ( L PO)水平 ,并与地勤人员进行比较。　结果　飞行员的血清 NO和L PO水平明显高于地勤人员 ,但 SOD水平却明显降低。　结论　飞行员的血清 NO水平和过氧化水平均明显升高 ,可能与一些疾病的发病机理有关 ,应采取相应对策。 Objective To study the effects of flight on serum nitric oxide (NO) and lipid peroxidation in pilots. Methods The serum NO, superoxide dismutase (SOD) and lipid peroxidation (L PO) of pilots were measured by α-naphthalene diamine spectrophotometry, xanthine oxidase method and thiobarbituric acid spectrophotometry. Level, and compared with the ground crew. Results Pilots’ serum NO and L PO levels were significantly higher than that of ground crew, but the levels of SOD were significantly decreased. Conclusion The pilot serum NO and peroxide levels were significantly elevated, which may be related to the pathogenesis of some diseases, and corresponding measures should be taken.