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【目的】了解景宁畲族自治县2~6岁儿童对乙型肝炎病毒的免疫状况,分析乙肝疫苗接种效果,为乙型肝炎防控提供依据。【方法】对2 660例在园儿童进行乙肝表面抗原、抗体,e抗原、抗体,c抗体检测,并对检出乙肝表面抗原阳性儿童进行回顾性调查。【结果】查出2~6岁儿童乙肝表面抗原阳性6人,乙肝表面抗体阳性1 778人,乙肝e抗原、抗体阳性6例,c抗体阳性5例;6例乙肝病毒携带儿童都有母亲是乙肝病毒携带者的病史。本县2~6岁儿童乙肝病毒携带率为0.23%,大大低于成人的携带率10%,乙肝表面抗体阳性率66.84%。【结论】乙肝疫苗对预防乙肝病毒感染是非常有效的,做好乙肝疫苗接种和防止母婴垂直传播可以有效预防儿童乙型肝炎病毒感染。
【Objective】 To understand the immune status of hepatitis B virus in children aged 2 ~ 6 in Jingning She Autonomous County, analyze the effect of hepatitis B vaccination and provide basis for hepatitis B prevention and control. 【Method】 The detection of hepatitis B surface antigen, antibody, e antigen, antibody and c antibody was performed on 2 660 children in the park. Retrospective investigation was made on the children with HBsAg positive. 【Results】 The results showed that there were 6 positive HBsAg in children aged 2 ~ 6 years, 1 778 HBsAg positive, 6 HBsAg positive, 6 antibody positive and 5 positive c antibody. Among the 6 HBsAg-positive children, History of hepatitis B virus carriers. The county children aged 2 to 6 years with hepatitis B virus carrier rate of 0.23%, significantly lower than the adult carrier rate of 10%, hepatitis B surface antibody positive rate of 66.84%. 【Conclusion】 Hepatitis B vaccine is very effective in preventing hepatitis B virus infection. Hepatitis B virus vaccination and prevention of mother-infant vertical transmission can effectively prevent hepatitis B virus infection in children.