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目的 观察高血压脑出血患者微创术前、后脑干听觉诱发电位 (BAEP)的变化 ,辅助评价微创术的疗效。方法 对 36例高血压脑出血患者进行微创术治疗 ,监测术前、术后 2 4,48,72h以及术后第 7天的BAEP改变。结果 本组存活 30例 ,6例死亡 ,死亡率为 16.7%。术前BAEP异常主要表现为潜伏期 (PL)及峰间潜伏期 (IPL)延长 ,与正常对照组相比 ,差异有显著性 (P <0 .0 5 )。术后 2 4h内复查 ,PL和IPL均有明显下降 ,与术前相比 ,差异有显著性意义 (P <0 .0 5 )。术后 48,72h和 7d复查BAEP ,与术前相比 ,PL和IPL虽然下降 ,但差异无明显统计学意义 (P >0 .0 5 ) ;与正常对照组相比 ,PL和IPL仍有延长 (P <0 .0 5 )。结论 微创术安全、有效。BAEP作为急性缺血、缺氧时脑干功能状态的一项检测指标可以用于高血压脑出血患者微创术前、后监测及预后评估
Objective To observe the changes of brainstem auditory evoked potentials (BAEP) in patients with hypertensive intracerebral hemorrhage before and after minimally invasive surgery to evaluate the curative effect of minimally invasive surgery. Methods Thirty-six patients with hypertensive intracerebral hemorrhage underwent minimally invasive surgery. The changes of BAEP before operation, at 2, 48, 72 hours and 7 days after operation were monitored. Results The group survived in 30 cases, 6 patients died, the mortality rate was 16.7%. Preoperative BAEP abnormalities mainly manifested as latency (PL) and peak latency (IPL) prolongation, compared with the normal control group, the difference was significant (P <0.05). Within 24 hours after operation, PL and IPL were significantly decreased compared with preoperative, the difference was significant (P <0. 05). At 48, 72, and 7 days postoperatively, BAEP was compared with that before operation, although there was no significant difference in PL and IPL between the two groups (P> 0.05). Compared with the control group, PL and IPL remained Extended (P <0. 05). Conclusion Minimally invasive surgery is safe and effective. BAEP as a marker of brainstem dysfunction in acute ischemia and hypoxia can be used to monitor pre-and post-monitoring and prognosis of patients with hypertensive intracerebral hemorrhage