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对2011年在上海真如社区内分泌门诊建档的718名糖尿病患者测定身高、体重、血压、糖化血红蛋白、血脂等,并实施免散瞳眼底摄片。视网膜病变的诊断依据2002年国际眼科会议和美国眼科学会联合制定的分级诊断标准。结果在718例糖尿病患者中,DR患病率为18.1%,其中轻、中及重度非增生性DR的患病率分别为12.1%、3.9%和1.8%,增生性DR患病率为0.3%。在病程5.1~10年、10.1~15年和>15年的糖尿病患者中,DR患病率分别为13.2%、24.5%和28.8%(P for trend<0.05)。多因素Logistic回归分析发现:在校正了性别、体重指数、血压及血脂后,糖尿病病程及糖化血红蛋白水平是糖尿病病人合并发生DR的独立危险因素。结论在上海社区2型糖尿病患者中,有近1/5患者存在不同程度DR,其中绝大多数为非增生性病变。糖尿病病程及血糖控制水平与糖尿病病人合并发生DR独立相关,提示社区医院医生应重视DR早期筛查和早期治疗。
To determine the height, weight, blood pressure, glycosylated hemoglobin, blood lipids, etc. of 718 diabetic patients who were filing in the endocrine clinic in Shanghai in 2011 as a real-time patient. The diagnosis of retinopathy is based on the staging diagnostic criteria jointly established by the 2002 International Eye Conference and the American Academy of Ophthalmology. Results Among 718 diabetic patients, the prevalence of DR was 18.1%. The prevalences of mild, moderate and severe non-proliferative DR were 12.1%, 3.9% and 1.8% respectively, and the prevalence of proliferative DR was 0.3% . The prevalence of DR was 13.2%, 24.5% and 28.8%, respectively, in patients with diabetes ranging in duration of 5.1 to 10 years, 10.1 to 15 years and> 15 years (P for trend <0.05). Multivariate logistic regression analysis found that after adjusting for gender, body mass index, blood pressure and blood lipids, diabetes course and HbA1c level were independent risk factors for DR in patients with diabetes mellitus. Conclusion In the Shanghai community, type 2 diabetes patients, there are nearly 1/5 of patients with varying degrees of DR, the vast majority of non-proliferative lesions. The duration of diabetes and the level of glycemic control were independently associated with DR in patients with diabetes mellitus, suggesting that community hospital doctors should pay attention to early screening and early treatment of DR.