迟发性维生素K缺乏症多合并颅内出血,延误治疗病死率高,且易留神经系统后遗症。本组母乳喂养儿14例占70％,提示单纯母乳儿发病率高,20例中合并颅内出血14例占70％,<24小时开始维生素K_1治疗者5例全部治愈,随访未发现神经系统后遗症;>48小时后确诊者及延误或拒绝治疗者死亡率高达20％,且50％遗留神经系统后遗症。维生素K_1对该病的预防及治疗效果均显著,预防用药每月肌注1mg,治疗每日10mg静注1次即可, Delayed vitamin K deficiency combined intracranial hemorrhage, delayed treatment of high mortality, and easy to stay nervous system sequelae. The group of breastfeeding children accounted for 70% of 14 cases, suggesting that the high incidence of breast-feeding alone, 20 cases of intracranial hemorrhage in 14 cases accounted for 70%, <24 hours vitamin K_1 treatment were 5 cases were cured, no neurological sequelae were found ; Those who were diagnosed after 48 hours and those who delayed or refused treatment had a mortality rate as high as 20% and 50% had neurological sequelae. Vitamin K_1 on the prevention and treatment of the disease are significant, prophylaxis intramuscular injection of 1mg per day, the treatment of intravenous injection of 10mg once a day,