Crosstalk between xenobiotic metabolism and energy metabolism in the liver has provided a potential opportunity to target xenobiotic receptors to treat metaboli
Targeting immune checkpoints such as programmed cell death protein 1(PD-1)and pro-grammed death ligand-1(PD-L1)have been approved for treating melanoma,gastric
As an effective anticancer drug,the clinical limitation of doxorubicin(Dox)is the time-and dose-dependent cardiotoxicity.Yes-associated protein 1(YAP1)interacts
Although interferon α(IFNα)and anti-angiogenesis antibodies have shown appropriate clin-ical benefit in the treatment of malignant cancer,they are deficient i
Alcoholic liver disease(ALD)causes insulin resistance,lipid metabolism dysfunction,and inflammation.We investigated the protective effects and direct regulating