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目的 :探讨多发性硬化症 (MS)临床特点。方法 :分析 2 0例MS患者临床特点 ,包括一般资料 ,定位诊断 ,重要辅助检查及治疗转归。结果 :MS多见于青壮年 ,女性略多 ,起病较急 ,病程多缓解复发 ,病毒感染为其主要诱因 ,脊髓、视神经受累多见 ,电生理及磁共振检查对诊断有帮助 ,糖皮质激素治疗有效 ,慢性者单用糖皮质激素效差 ,部分病例合用丙种球蛋白则可提高疗效。结论 :根据临床特点 ,综合免疫学 ,神经电生理及影像学检查 ,能大大提高临床确诊率 ,MS分期有助于判断疾病的预后和转归。
Objective: To investigate the clinical features of multiple sclerosis (MS). Methods: The clinical features of 20 MS patients were analyzed, including general data, location diagnosis, important auxiliary examination and treatment outcome. Results: MS more common in young adults, slightly more women, more acute onset, relapse and more disease course, the main cause of viral infection, spinal cord, optic nerve involvement more common, electrophysiological and magnetic resonance imaging to help diagnose, glucocorticoid Effective treatment, chronic glucocorticoid single effect poor, in some cases with gamma globulin can improve the curative effect. Conclusion: According to clinical features, comprehensive immunology, neuroelectrophysiology and imaging examination can greatly improve the clinical diagnosis rate, MS staging helps to determine the prognosis and outcome of the disease.