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生物液体样品如血浆与尿通常要经过样品制备除去内源性干扰物并加以浓缩后方可作色谱分析.近年来样品制备的突出进展是使用固相提取(SPE)或液-固提取(LSE)法来取代传统的液液提取.将分析物从生物试样内提取到装在易于处理的商品芯子(Cartridge)内的固相材料如硅胶或键合硅胶上,然后用适当的洗脱方法将干扰物含量减少到极小.通常认为如使用C_(1?)键合硅胶来提取,起支配作用的应该是反相机制,然而作者通过预试验认为可能存在其他更重要
Biological liquid samples, such as plasma and urine, are usually subjected to sample preparation to remove endogenous interferors and concentrate them for chromatographic analysis.Optimum progress in sample preparation in recent years has been the use of solid phase extraction (SPE) or liquid-solid extraction (LSE) Method to replace traditional liquid-liquid extraction.The analyte is extracted from the biological sample into a solid-phase material such as silica gel or bonded silica gel packed in a disposable cartridge and then eluted with a suitable elution method The interfering substances are minimized.It is generally believed that the use of C_ (1?) Bonded silica gel to extract, the dominant role should be anti-phase mechanism, but the author through pre-test that there may be other more important