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未足月胎膜早破是指妊娠不满37周时,胎膜在临产前发生自发性破裂,是最常见的妊娠期并发症之一[1],容易导致母婴预后不良。对于妊娠≥34周胎膜早破,一般采取促胎肺成熟后引产,以防止因继续期待治疗而增加宫内感染发生风险,以及引起围生儿和产妇并发症。地诺前列酮栓(商品名:欣普贝生)是欧美国家晚期引产前促宫颈成熟首选药物[2]。目前,国内外有关妊娠34～36+6周胎膜早破产妇应用地诺前列酮栓的报道较少。2009年3月-2011年8月,我们对未足月胎膜早破产妇37例,采用地诺前列酮栓促宫颈成熟及引产。现分析报告如下。
Premature rupture of membranes refers to premature rupture of membranes at 37 weeks of gestation, fetal membranes in prenatal spontaneous rupture, is one of the most common complications of pregnancy [1], easily lead to poor maternal and child prognosis. For preterm premature rupture of membranes at ≥34 weeks of gestation, induction of labor is generally adopted to promote maturation of the fetal lung to prevent the risk of intrauterine infection from continuing to be treated and to cause perinatal and maternal complications. Dinoprostone suppository (trade name: Hinbu Beisen) is the first choice for cervical ripening before induction of labor in Europe and the United States [2]. At present, there are few reports about the application of droperidol suppository in preterm premature rupture of membranes in 34 ~ 36 + 6 weeks gestation. From March 2009 to August 2011, 37 cases of preterm premature rupture of membranes were treated with dinoprostone to promote cervical ripening and induction of labor. The analysis report is as follows.