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目的:观察奥扎格雷钠联合氯吡格雷对不稳定型心绞痛的疗效与安全性。方法:将56例不稳定型心绞痛患者随机分为治疗组和对照组,两组均给予阿司匹林等常规治疗。治疗组在对照组基础上加用奥扎格雷钠注射液、氯吡格雷。两组疗程均2周,观察两组的临床疗效及安全性。结果:治疗组心绞痛发作频率、疼痛程度明显减轻,疼痛时间缩短,心电图缺血性ST段的改善明显优于对照组(P<0.05),且未发现有出血等不良反应。结论:奥扎格雷钠、氯吡格雷联合应用治疗不稳定型心绞痛疗效显著。
Objective: To observe the efficacy and safety of ozagrel combined with clopidogrel in patients with unstable angina pectoris. Methods: 56 patients with unstable angina were randomly divided into treatment group and control group. Both groups were given routine treatment such as aspirin. The treatment group was given Ozagrel sodium injection and clopidogrel on the basis of the control group. Two courses of treatment were 2 weeks, observe the clinical efficacy and safety of the two groups. Results: The frequency of angina pectoris, the severity of pain and the shortened pain time in the treatment group were significantly better than those in the control group (P <0.05). No adverse reactions such as hemorrhage were found. Conclusion: Ozagrel and clopidogrel are effective in treating unstable angina pectoris.