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[目的]探讨高钠血症对各种颅脑损伤预后的影响。[方法]对203例不同原因所致的脑损伤患者的临床资料进行分析,记录病情发展过程中血钠的变化值以及出现高钠血症的时间,将所得数值与患者的预后进行相关性分析,并进行统计学处理。[结果]203例颅脑损伤患者中有68例并发高钠血症,伴高钠血症患者的预后明显较不伴高钠血症者差,P﹤0.05;在颅脑损伤后72h以上并发高钠血症的患者预后较24h以内或24～72h并发者差,P值分别﹤0.05或﹤0.001;而高血钠发生在24h以内者与发生在24～72h者的预后差异无统计学意义(P﹥0.05)。[结论]颅脑损伤后出血高钠血症预示着患者的预后不佳,且出现时间越晚,预后越差,临床上对这类患者需提高警惕。
[Objective] To investigate the effect of hypernatremia on the prognosis of various brain injury. [Methods] The clinical data of 203 patients with brain injury caused by different causes were analyzed. The change of serum sodium and the time of occurrence of hypernatremia were recorded, and the correlation between the value and the prognosis of patients was analyzed , And statistical processing. [Results] Sixty-three of the 203 patients with craniocerebral injury developed hypernatremia. The prognosis of patients with hypernatremia was significantly worse than that of patients without hypernatremia (P <0.05). In the group of more than 72 hours after craniocerebral injury The prognosis of patients with hypernatremia than 24h or 24 ~ 72h complicated by poor, P values were <0.05 or <0.001; and hyperuricemia occurred within 24 hours in patients with 24 to 72 h in the prognosis was no significant difference (P> 0.05). [Conclusion] The hypernatremia of hemorrhage after craniocerebral injury indicates the poor prognosis of patients. The later the time is, the worse the prognosis is. Clinic should be vigilant for such patients.