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目的观察晚期胃腺癌患者术中及术后的相关指标,探讨肥胖对患者术后结局的影响。方法回顾性分析近5年于某院实施手术治疗的226例晚期胃腺癌患者的临床资料,根据体重指数(BMI)将胃腺癌患者分为非肥胖组和肥胖组,非肥胖组134例患者BMI﹤25,肥胖组92例患者BMI≥25,两组患者均行胃腺癌根治术,观察记录两组术的中出血量、手术时间、肛门排气时间、术后并发症、术后引流量、住院死亡率及随访记录患者一年生存率。结果 BMI﹤25组与BMI≥25组患者的肛门排气时间、住院死亡率、一年生存率对比差异无统计学意义(P﹥0.05);BMI﹤25组的术中出血量、手术时间、术后引流量、术后并发症分别为(223.2±136.6)ml、(158.1±57.9)min、(281.5±174.6)ml、11.2%,BMI≥25组分别为(266.9±170.1)ml、(188.2±79.7)min、(348.0±209.3)ml、21.7%,P﹤0.05。结论肥胖对于患者术后的住院死亡率及一年生存率等短期结局无明显影响,不改变晚期胃腺癌患者的术后结局。
Objective To observe the intraoperative and postoperative related indexes of patients with advanced gastric adenocarcinoma and to investigate the effect of obesity on the postoperative outcome of patients. Methods The clinical data of 226 patients with advanced gastric adenocarcinoma who underwent surgery in a hospital in recent 5 years were retrospectively analyzed. According to the body mass index (BMI), patients with gastric adenocarcinoma were divided into non-obese group and obesity group. The non-obese group of 134 patients with BMI <25, 92 patients with obesity group BMI ≥ 25, both patients underwent gastric adenocarcinoma radical surgery, the two groups were observed in the amount of bleeding, operation time, anal exhaust time, postoperative complications, postoperative drainage, In-hospital mortality and follow-up recorded one-year survival rate of patients. Results There was no significant difference in anal exhaust time, in-hospital mortality rate and one-year survival rate between BMI group <25 and BMI group> 25 (P> 0.05). The blood loss, operation time, The postoperative drainage and postoperative complications were (223.2 ± 136.6) ml, (158.1 ± 57.9) min, (281.5 ± 174.6) ml and 11.2%, and those with BMI≥25 were (266.9 ± 170.1) ml and ± 79.7) min, (348.0 ± 209.3) ml, 21.7%, P <0.05. Conclusion Obesity has no significant effect on short-term outcomes such as in-hospital mortality and one-year survival rate after operation, and does not change the postoperative outcome in patients with advanced gastric adenocarcinoma.