吡唑类化合物具有良好的生物活性,其被广泛应用于农药领域。由于氟原子具有电子效应、阻碍效应和渗透效应等特殊的性质,把氟原子和含氟基团引入到具有生物活性的吡唑类化合物中,能大大地提高其生物活性。因此,含氟吡唑类化合物的合成一直受到国内外研究人员的关注。就含氟吡唑类化合物合成方法的研究进展进行了总结。 Pyrazole compounds have good biological activity, which is widely used in the field of pesticides. Due to the special properties of fluorine atom such as electron effect, hindering effect and infiltration effect, the introduction of fluorine atoms and fluorine-containing groups into biologically active pyrazole compounds can greatly enhance their biological activity. Therefore, the synthesis of fluorine-containing pyrazole compounds has been the concern of researchers at home and abroad. The research progress of synthesis methods of fluorine-containing pyrazole compounds are summarized.